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Fetal Alcohol Syndrome: An Examination of Craniofacial Dysmorphology in Macaca nemestrina
Author(s) -
Inouye Randall N.,
Kokich Vincent G.,
Clarren Sterling K.,
Bowden Douglas M.
Publication year - 1985
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.1985.tb00169.x
Subject(s) - macaca nemestrina , craniofacial , craniofacial abnormality , primate , anatomy , fetal alcohol syndrome , in utero , nonhuman primate , fetus , medicine , synostosis , sagittal plane , biology , pregnancy , macaque , neuroscience , genetics , psychiatry , evolutionary biology
The purpose of this investigation was to evaluate the craniofacial features in nonhuman primate models exposed in utero to moderate and high weekly binge doses of ethanol. While the high‐dosed animal did have unusual craniofacial dysmorphology, she did not exhibit the typical facial pattern seen in human fetal alcohol syndrome. The high‐dosed specimen displayed a scaphocephalic head shape secondary to synostosis of the sagittal suture. The brain of this monkey was grossly abnormal and microcephalic