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Hemodynamic and Endocrine Parameters in the Anesthetized Cynomolgus Monkey: A Primate Model
Author(s) -
Udelsman Robert,
Bather John,
Gallucci William T.,
Cold Philip W.,
Morin Martin L.,
Renquist David,
Loriaux D. Lynn,
Chrousos George P.
Publication year - 1984
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.1984.tb00156.x
Subject(s) - primate , hemodynamics , endocrine system , nonhuman primate , non human primate , biology , medicine , anesthesia , neuroscience , hormone , evolutionary biology
Hemodynamic and endocrine parameters were determined in nine anesthetized adult male cynomolgus monkeys. Simultaneous phasic and mean pressures were measured in the right artrium, pulmonary artery, and abdominal aorta. Intermittent pulmonary artery wedge pressures and mean cardiac output measured by the thermal dilution method were used to calculate stroke volume, systemic vascular resistance, and pulmonary vascular resistance. Plasma adrenocorticotropic hormone (ACTH), cortisol, and plasma renin activity were measured throughout the procedure. Technical aspects, data in the anesthetized monkey, and comparison with previously reported data are presented.