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Lipid Composition of the Peripheral Nerves in Malnutrition: An Experimental Study in Young Rhesus Monkeys
Author(s) -
Rana S.V.,
Mehta S.,
Chopra J.S.,
Nain C.K.,
Dhand U.K.,
Mehta J.
Publication year - 1984
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.1984.tb00138.x
Subject(s) - peripheral , malnutrition , composition (language) , physiology , anatomy , medicine , biology , pathology , endocrinology , philosophy , linguistics
An experimental model of protein calorie malnutrition (PCM) was created in young rhesus monkeys. Ulnar and tibial nerves from six monkeys with PCM, six rehabilitated and 12 control monkeys were studied for lipid composition and activity of myelin marker enzyme. Total lipids, myelin marker lipids and activity of myelin marker enzyme, 2′, 3′‐cyclic nucleotide 3′ ‐ phosphohydrolase were decreased, while esterified cholesterol and free fatty acids were increased in PCM as compared to controls. There was partial recovery in myelin marker lipids and complete restoration of other lipids on nutritional rehabilitation.