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Effects of Primaquine on Serum Biochemical and Hematological Parameters in Anesthetized Macaca fascicularis
Author(s) -
Kapeghian John C.,
Verlangieri Anthony J.
Publication year - 1984
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.1984.tb00119.x
Subject(s) - primaquine , uric acid , calcium , medicine , pharmacology , biology , endocrinology , malaria , immunology , chloroquine
Primaquine phosphate treatment (0.5 mg/kg/day, per os [p.o.], 14 days) significantly increased values for serum sodium, potassium, and uric acid, while calcium levels were decreased in male Macaca fascicularis. Serum values returned to baseline (pretreatment) levels by 30 days following primaquine treatment.