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Standardization of Anaesthesia for Radiorenography With Primates Under Laboratory Conditions
Author(s) -
Dormehl Irene C.,
Jacobs D.J.,
Plessis Maryke du,
Goosen D.J.
Publication year - 1984
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.1984.tb00104.x
Subject(s) - standardization , anesthesia , medicine , biology , computer science , operating system
The influence of thiopentone intravenous infusion or halothane inhalation on the results of radiorenography was evaluated using, in six chacma baboons ( Papio ursinus ), 99m Tc‐diethyltriamine‐pentaacetic acid (DTPA) as scanning agent. The renogram parameters, which depend on the condition of the cardiovascular system, differed significantly for the two anaesthetic agents. Since anaesthesia is necessary in baboon studies for the duration of renogram acquisition, it is imperative to standardize an experimental procedure which will leave the cardiovascular system relatively stable. From this investigation it seemed most appropriate to use as an anaesthetic a constant intravenous infusion of thiopentone.