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Imaging host–pathogen interactions
Author(s) -
Campisi Laura,
Brau Frédéric,
Glaichenhaus Nicolas
Publication year - 2008
Publication title -
immunological reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.839
H-Index - 223
eISSN - 1600-065X
pISSN - 0105-2896
DOI - 10.1111/j.1600-065x.2008.00586.x
Subject(s) - decipher , biology , host (biology) , pathogen , computational biology , salmonella , data science , computer science , bioinformatics , immunology , genetics , bacteria
Summary: Imaging techniques have been revolutionized by advancements in both microscope instrumentation and data collection processing software. Immunologists and microbiologists now have access to a large panel of powerful technologies that are characterized by different spatial and time resolutions. In this review, we discuss recent studies in which emerging imaging technologies have been used to decipher the complexity of the interactions between pathogens and their mammalian hosts. By focusing on two very different pathogens, Plasmodium and Salmonella , we emphasize the critical role of imaging studies in the understanding of the host's immune system response to a pathogen.