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Successful use of cyclophosphamide, bortezomib, and dexamethasone to treat a case of relapsed POEMS
Author(s) -
Warsame Rahma,
Kohut Ingrid E.,
Dispenzieri Angela
Publication year - 2012
Publication title -
european journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0902-4441
DOI - 10.1111/j.1600-0609.2012.01780.x
Subject(s) - dexamethasone , bortezomib , cyclophosphamide , medicine , oncology , multiple myeloma , chemotherapy
POEMS syndrome is a rare paraneoplastic condition related to myeloma. Because it is rare, there is very little known about treatment options. The use of potentially neurotoxic chemotherapeutic drugs is of concern in a disease whose major manifestation is neuropathy. Herein, we describe an extraordinary response to the combination of cyclophosphamide, bortezomib, and dexamethasone (CyBorD) in a patient with relapsed, life‐threatening POEMS syndrome.