Successful use of cyclophosphamide, bortezomib, and dexamethasone to treat a case of relapsed POEMS | Zendy

Warsame Rahma | Zendy; Kohut Ingrid E. | Zendy; Dispenzieri Angela | Zendy

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Successful use of cyclophosphamide, bortezomib, and dexamethasone to treat a case of relapsed POEMS

Author(s) -

Warsame Rahma,

Kohut Ingrid E.,

Dispenzieri Angela

Publication year - 2012

Publication title -

european journal of haematology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.904

H-Index - 84

eISSN - 1600-0609

pISSN - 0902-4441

DOI - 10.1111/j.1600-0609.2012.01780.x

Subject(s) - dexamethasone , bortezomib , cyclophosphamide , medicine , oncology , multiple myeloma , chemotherapy

POEMS syndrome is a rare paraneoplastic condition related to myeloma. Because it is rare, there is very little known about treatment options. The use of potentially neurotoxic chemotherapeutic drugs is of concern in a disease whose major manifestation is neuropathy. Herein, we describe an extraordinary response to the combination of cyclophosphamide, bortezomib, and dexamethasone (CyBorD) in a patient with relapsed, life‐threatening POEMS syndrome.

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