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PET‐CT imaging of combined brachial and lumbosacral neurolymphomatosis
Author(s) -
Kanter Pazit,
Zeidman Aliza,
Streifler Jonathan,
Marmelstein Victor,
EvenSapir Einat,
Metser Ur,
Stein Gideon Y.,
Cohen Amos M.
Publication year - 2005
Publication title -
european journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0902-4441
DOI - 10.1111/j.1600-0609.2004.00369.x
Subject(s) - medicine , vincristine , lumbosacral joint , radiology , lymphoma , rituximab , magnetic resonance imaging , diffuse large b cell lymphoma , positron emission tomography , prednisone , cyclophosphamide , nuclear medicine , chemotherapy , pathology , surgery
Neurolymphomatosis is a rare manifestation of progressive non‐Hodgkin's lymphoma. A 44‐yr‐old man with diffuse large B‐cell lymphoma presented with unilateral progressive peripheral sensorimotor neuropathy after the 7th cycle of R‐CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone) therapy. No pathology in the nervous system was evident by computerized tomography (CT), magnetic resonance imaging (MRI) of the head, spinal axis and plexuses and by repeated analysis of cerebrospinal fluid. However, the hybrid modality of positron emission tomography (PET) of fluorinated deoxyglucose (FDG) combined with CT scan (PET‐CT) showed unilateral involvement of both the brachial and lumbosacral nervous plexuses. A complete recovery of neurological manifestations and normalization of PET‐CT followed intensive chemotherapy with autologous stem cell transplantation. The diagnosis and localization of neurolymphomatosis may be supported by PET‐CT imaging.