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A case of disseminated Langerhans’ cell histiocytosis treated with thalidomide
Author(s) -
Mauro E.,
Fraulini C.,
Rigolin G. M.,
Galeotti R.,
Spanedda R.,
Castoldi G.
Publication year - 2005
Publication title -
european journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0902-4441
DOI - 10.1111/j.1600-0609.2004.00358.x
Subject(s) - langerhans cell histiocytosis , thalidomide , medicine , histiocytosis , dermatology , pathology , immunology , multiple myeloma , disease
Tumor necrosis factor alpha (TNF‐ α ) seems to play a key role in the pathogenesis of Langerhans’ cell histiocytosis (LCH). Thalidomide is an immunomodulator agent of inflammatory cytokines including TNF‐ α . To our knowledge this is the first case of disseminated LCH successfully treated with thalidomide.