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Pregnancy‐associated aplastic anemia ‐Report of 3 cases
Author(s) -
Besien Koen,
Tricot Guido,
Golichowski Alan,
Padilla Lillie,
Hoffman Ronald
Publication year - 1991
Publication title -
european journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0902-4441
DOI - 10.1111/j.1600-0609.1991.tb01567.x
Subject(s) - pancytopenia , medicine , pregnancy , aplastic anemia , anemia , bone marrow transplantation , pediatrics , disease , surgery , obstetrics , bone marrow , transplantation , genetics , biology
3 patients with pregnancy‐associated aplastic anemia are reported. Management throughout most of the pregnancy consisted of supportive care. In 2 patients an improvement in blood counts occurred after delivery and, in 1 of these, the pancytopenia recurred during a subsequent pregnancy. In 1 case no improvement occurred after delivery and the patient ultimately required an allogeneic bone marrow transplantation. The outcome of these 3 cases demonstrates that pregnancy‐associated aplastic anemia can be managed successfully. The improvement that often occurs after delivery suggests a pathogenetic role for pregnancy in the development of this disease.