Premium
Structural chromosomal abnormalities of 3q in myelodysplastic syndrome/acute myeloid leukaemia with Sweet's syndrome
Author(s) -
Billström R.,
Heim S.,
Kristoffersson U.,
Mandahl N.,
Mitelman F.
Publication year - 1990
Publication title -
european journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0902-4441
DOI - 10.1111/j.1600-0609.1990.tb00442.x
Subject(s) - myeloid leukaemia , medicine , myeloid , bone marrow , myelodysplastic syndromes , chromosome , sweet's syndrome , pathology , karyotype , cancer research , immunology , biology , gene , genetics
Structural rearrangements in the long arm of chromosome 3, del(3)(q12q25) and t(3;5)(q21–25;q31–33), were observed in bone marrow cells from 2 patients with myeloid neoplastic disorders (myelodysplastic syndrome and acute myeloid leukaemia) and acute febrile neutrophil dermatosis (Sweet's syndrome). 3 of the 4 patients with leukaemia‐associated Sweet's syndrome and acquired chromosome abnormalities known from the literature also had 3q changes, in 2 involving band 3q21.