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Chronic myelomonocytic leukemia with chromosomal changes involving lp36 and hepatocellular carcinoma in a case of Fanconi's anemia
Author(s) -
Bessho Fumio,
Mizutani Shuki,
Hayashi Yasuhide,
Moriwaki Kohichi,
Yokota Shunichiro,
Inaba Toshiya
Publication year - 1989
Publication title -
european journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0902-4441
DOI - 10.1111/j.1600-0609.1989.tb01476.x
Subject(s) - chronic myelomonocytic leukemia , chromosomal translocation , hepatocellular carcinoma , fanconi anemia , leukemia , medicine , cancer research , anemia , bone marrow , acute myelomonocytic leukemia , pathology , immunology , biology , myelodysplastic syndromes , genetics , gene , dna repair
A girl with Fanconi's anemia developed chronic myelomonocytic leukemia and hepatocellular carcinoma. At the time that chronic myelomonocytic leukemia was diagnosed, all metaphases of the bone marrow cells revealed a chromosomal translocation involving 1p36. It is suggested that the occurrence of this rare type of leukemia in our patient is related to the chromosomal translocation.