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Regression of intracerebral lesions in T prolymphocytic leukaemia treated with intravenous deoxycoformycin
Author(s) -
BritoBabapulle Finella,
Huang David,
Lavender Peter,
Galton David,
Catovsky Daniel
Publication year - 1988
Publication title -
european journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0902-4441
DOI - 10.1111/j.1600-0609.1988.tb00819.x
Subject(s) - pentostatin , medicine , deoxycoformycin , prolymphocytic leukemia , intracerebral hemorrhage , confusion , nuclear medicine , radiology , adenosine , leukemia , psychology , chronic lymphocytic leukemia , subarachnoid hemorrhage , psychoanalysis , adenosine deaminase
A case of T‐prolymphocytic leukaemia (T‐PLL) presenting with deafness and confusion is reported. Computerised tomography (CT) of the head showed several well‐defined, rounded, high attenuation areas in the temporal, parietal and occipital regions of the brain substance that were suggestive of metastases. Treatment with weekly intravenous deoxycoformycin produced complete resolution of the CT abnormalities together with haematological evidence of disease regression 6 weeks after treatment was started.