Premium
Plasma fibronectin levels during daily plasmapheresis
Author(s) -
Wahlin Anders,
Holm Jan,
Hansson Mona,
Berghem Lars
Publication year - 1987
Publication title -
european journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0902-4441
DOI - 10.1111/j.1600-0609.1987.tb01421.x
Subject(s) - plasmapheresis , fibronectin , plasma concentration , multiple myeloma , fibronectins , chemistry , medicine , plasma levels , endocrinology , immunology , biochemistry , antibody , cell
Plasma fibronectin concentrations were studied in 10 patients with multiple myeloma. After plasma exchange for 3 d (2.5‐3 1 plasma daily) the plasma fibronectin decreased to about 50% of the initial level. Resynthesis of fibronectin seemed to increase during 3 d of plasmapheresis, and was sufficient to normalize plasma fibronectin concentration. The plasma fibronectin concentration reached the initial level within 2 d after interrupting plasmapheresis in spite of concurrent cytotoxic treatment. The patients studied showed no signs of infection.