Premium
Alpha interferon in the treatment of symptomatic myelofibrosis with myeloid metaplasia
Author(s) -
Parmeggiani L.,
Ferrant A.,
Rodhain J.,
Michaux J. L.,
Sokal G.
Publication year - 1987
Publication title -
european journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0902-4441
DOI - 10.1111/j.1600-0609.1987.tb00762.x
Subject(s) - myelofibrosis , medicine , metaplasia , myeloid , spleen , alpha interferon , bone marrow , gastroenterology , fibrosis , interferon , pathology , interferon alfa , immunology
2 patients with myelofibrosis and myeloid metaplasia had symptomatic splenomegaly and were treated with interferon alpha‐2c (IFN alpha‐2c). The splenic pain and pressure symptoms disappeared, accompanied by a decrease in the size of the spleen. However, the peripheral blood count worsened and no improvement in the bone marrow fibrosis could be observed.