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Benign monoclonal gammopathy presenting with severe renal failure
Author(s) -
Gavarotti Paolo,
Fortina Felice,
Costa Daniela,
Verzetti Giuseppe,
Redoglia Valter,
Boccadoro Mario
Publication year - 1986
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1986.tb02661.x
Subject(s) - monoclonal gammopathy , medicine , paraproteinemias , multiple myeloma , dermatology , pathology , intensive care medicine , monoclonal , monoclonal antibody , immunology , antibody
A patient with monoclonal gammopathy and renal failure due to K light chain deposition in the glomerular basement membrane is reported. After 8 months, he developed a progressive and severe renal failure requiring haemodialysis. 30 months later, the monoclonal gammopathy was unchanged. Clinical features, as well as kinetic and immunological studies, were consistent with a diagnosis of benign monoclonal gammopathy (BMG). This case suggests that the renal failure complicating a monoclonal gammopathy is not related to its malignancy.