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Neutrophil glutathione peroxidase activity in iron deficiency anaemia
Author(s) -
Sevgi Yetgin,
Goneng Ciliv,
Qigdem Altay
Publication year - 1986
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1986.tb02650.x
Subject(s) - glutathione peroxidase , peroxidase , iron deficiency , iron therapy , glutathione , medicine , immunology , gastroenterology , endocrinology , chemistry , anemia , enzyme , biochemistry
Neutrophil glutathione peroxidase (GSH‐PX) activity was studied in 30 children with nutritional iron deficiency anaemia and 25 healthy age‐matched controls. Initially GSH‐P, in iron deficient anaemic children was significantly (p < 0.001) low compared to the control group. All patients were subjected to iron therapy but only 8 returned for follow‐up. The GSH‐PX activity in all 8 cases rose to normal levels after therapy. These results suggest a relationship between iron and GSH‐P, activity.