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Non‐Hodgkin malignant lymphomas and Hodgkin's disease in first‐degree relatives
Author(s) -
Bjerrum Ole W.,
Hasselbalch Hans C.,
Drivsholm Aage,
Nissen Nis. I.
Publication year - 1986
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1986.tb01756.x
Subject(s) - lymphoma , disease , malignant lymphoma , medicine , genetic predisposition , first degree relatives , pathology , oncology , family history
The occurrence of malignant lymphomas in 3 siblings is described. The cases include the first report of Hodgkin's disease and non‐Hodgkin malignant lymphoma in dizygotic twins. Another remarkable feature was the development of malignant lymphoma, when the siblings were at the same age. Although a transmissible agent or environmental factors cannot be excluded in this family, our observations may suggest a mutual genetic predisposition in Hodgkin's disease and non‐Hodgkin malignant lymphoma.