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SIDEROBLAST COUNT AND EXAMINATION OF BONE MARROW RETICULOENDOTHELIAL IRON IN THE DIAGNOSIS OF IRON DEFICIENCY
Author(s) -
Rybo Elisabeth,
Bengtsson Calle
Publication year - 1985
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1985.tb00788.x
Subject(s) - mononuclear phagocyte system , bone marrow , transferrin saturation , iron deficiency , pathology , medicine , population , physiology , immunology , anemia , environmental health
Bone marrow smears from 38‐year‐old women participating in a population study were examined with respect to stainable iron in reticuloendothelial cells and in erythroblasts called sideroblasts. Blood haemoglobin concentration, erythrocyte mean corpuscular haemoglobin and transferrin saturation in serum were lower in women with no stainable iron in the reticuloendothelial cells and sideroblast counts below 16 % than in women with stainable iron clearly visible and sideroblast counts equal to or above 16 %. Iron absorption was higher and menstrual blood loss heavier in women with no iron than in women with stainable iron, irrespective of the number of sideroblasts. Examination of reticuloendothelial iron was a more effective method for defining iron deficient subjects than was the counting of sideroblasts.