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QUALITY CONTROL OF THE ONE‐STAGE FACTOR VIII (VIII:C) ASSAY IN THE COAGULATION LABORATORY
Author(s) -
Over Jan
Publication year - 1984
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1984.tb02770.x
Subject(s) - reliability (semiconductor) , quality (philosophy) , coagulation , reliability engineering , stage (stratigraphy) , control (management) , test (biology) , factor ix , chemistry , computer science , chromatography , engineering , medicine , biology , biochemistry , artificial intelligence , paleontology , philosophy , power (physics) , physics , epistemology , quantum mechanics
In this chapter measures are described that should be taken to ensure the reliability and accuracy of one‐stage assays of Factor VIII coagulant activity (VIII:C). The first part deals with requirements for reagents, test conditions and procedure. The second half is dedicated to the problem of interlaboratory variation of Factor VIII assays; the results of a multicentre collaborative study on the quality control of Factor VIII concentrates are presented.