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Centrifugal and anticoagulant induced variations in platelet rich plasma and their influence on platelet aggregation
Author(s) -
HEALY DAVID T.,
EGAN ERNEST L.
Publication year - 1984
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1984.tb02184.x
Subject(s) - platelet , platelet aggregation , platelet rich plasma , chemistry , anticoagulant , function (biology) , biophysics , medicine , biology , microbiology and biotechnology
Variations in the centrifugal force (g) used to prepare platelet‐rich‐plasma (PRP) alter not only the number of platelets therein but also their size and reactivity. Anticoagulants also affect these parameters. According we suggest that PRP preparations need to be strictly standardised. Critical comment on the use of the platelet aggregation model as a means of assessing 5‐hydroxytryptamine receptor function is included.