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Exercise‐Induced Changes in the in Vivo Distribution of 111 In‐Labelled Platelets
Author(s) -
Schmidt Kai Gjerløff,
Rasmussen Jens Wæver
Publication year - 1984
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1984.tb02172.x
Subject(s) - platelet , thrombocytosis , in vivo , spleen , medicine , chemistry , endocrinology , pathology , biology , microbiology and biotechnology
In order to throw some light on the mechanisms underlying exercise‐induced thrombocytosis, we investigated 15 healthy persons subjected to short‐term vigorous pedalling on a bicycle ergometer 1 d after injection of autologous 111 In‐labelled platelets. Scintigraphic studies during the post‐exercise period showed the spleen to be the major platelet‐releasing organ. There was, however, a considerable interindividual variability manifested as signs of a contributing platelet release from the lungs in some cases and of deposition of a surplus of released platelets in the liver of others. Our results also seem to be compatible with the existence of an intravascular marginal platelet pool.