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Critical Study of Staging in Multiple Myeloma
Author(s) -
Pennec Yvon,
Mottier Dominique,
Youinou Pierre,
Asselain Bernard,
Chavance Michel,
Goff Paul Le,
Prise PierreYves Le,
Miossec Pierre,
Menn Gabriel Le
Publication year - 1983
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1983.tb01468.x
Subject(s) - multiple myeloma , medicine , overall survival , retrospective cohort study , bone marrow , gastroenterology , significant difference , stage (stratigraphy) , biology , paleontology
130 patients with multiple myeloma were revieved for a retrospective study of their classification according to Durie & Salmon. No significant difference was found in survival between patients in stages I, II and III (median survival 24.8, 32.1, and 17.3 months, respectively). Of the classical criteria affecting survival, only the Hb level showed any significant influence (P < 0.04). In accordance with this finding, the survival time was much shorter (P < 0.001) in patients with renal failure than in patients without (median survival 7.4 and 24.8 months, respectively); in addition, thrombopenia, fever, old age, and above all, the % of bone‐marrow plasmocytes present, were shown to be decisive factors.