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Amrinone‐Mediated Thrombocytopenia
Author(s) -
Kinney Evlin L.,
Ballard James O.,
Carlin Brian,
Zelis Robert
Publication year - 1983
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1983.tb00665.x
Subject(s) - amrinone , medicine , heart failure , cardiology , adverse effect , platelet
Amrinone, a new cardioactive drug, was administered for, on average, 27.9 d to 12 patients in severe congestive heart failure. Thrombocytopenia occurred in 4 patients, while a progressive decline in platelet numbers developed in 3 additional patients. The mechanism for these adverse effects of amrinone is unclear, but merits further study because of its frequency.