Premium
Cytomegalovirus Encephalitis Occurring after Bone Marrow Transplantation
Author(s) -
Cordonnier C.,
Feuilhade F.,
Vernant J. P.,
Marsault C.,
Rodet M.,
Rochant H.
Publication year - 1983
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1983.tb00648.x
Subject(s) - bone marrow transplantation , cytomegalovirus , encephalitis , virology , transplantation , medicine , bone marrow , cytomegalovirus infections , pathology , immunology , human cytomegalovirus , herpesviridae , virus , viral disease
4 months after a bone marrow transplantation performed for acute lymphocytic leukaemia, a 28‐year‐old man had encephalitis. A brain CT scan revealed bilateral and symmetrical temporal hypodense areas. Serological studies revealed a recent CMV conversion in serum and a higher conversion in cerebral spinal fluid. All other viral antibodies remained at low levels, especially for herpes simplex virus. Because of a high incidence of CMV infection after bone marrow transplantation, the responsability of CMV as the cause of the encephalitis is discussed.