Premium
Iron Overload in a Non‐Transfused Patient with Thalassaemia Intermedia
Author(s) -
Celada Antonio
Publication year - 1982
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1982.tb00510.x
Subject(s) - erythropoiesis , ineffective erythropoiesis , thalassemia , medicine , beta thalassemia , intermedia , anemia , hemosiderosis , hemochromatosis , absorption (acoustics) , gastroenterology , physics , acoustics , art , performance art , art history
A patient with thalassaemia intermedia and haemosiderosis is reported. This patient did not receive transfusions or iron therapy. The iron absorption and the plasma iron turnover (PIT) were increased. Transfusions were carried out in order to decrease the amount of abnormal erythropoiesis. After that, the erythropoietin and PIT were decreased to normal levels and the iron absorption also returned to normal. The data presented suggest that increased erythropoiesis was responsible for the abnormaly high iron absorption and subsequently for the haemosiderosis of the patient presented.