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Serum Vitamin B 12 and Erythrocyte Folate in Chronic Uraemia and after Renal Transplantation
Author(s) -
Milman Nils
Publication year - 1981
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1981.tb01380.x
Subject(s) - medicine , gastroenterology , transplantation , peritoneal dialysis , renal function , chronic renal failure , vitamin b , endocrinology , vitamin
Serum B 12 and erythrocyte folate were measured in 16 non‐dialysed uraemic patients, 28 peritoneal dialysed patients, 28 haemodialysed patients, 14 renal transplanted patients with normal renal function and 49 healthy control subjects. Serum B 12 values in non‐dialysed uraemic patients were higher than in control subjects (P < 0.001), peritoneal dialysed (P < 0.05), and transplanted patients (P < 0.01). Serum B 12 values in peritoneal dialysed, haemodialysed and transplanted patients were not significantly different from the control group. Erythrocyte folate values in non‐dialysed uraemic patients were lower than in controls (P < 0.03), but all subjects had values within the normal range. Erythrocyte folate values in peritoneal dialysed, haemodialysed and renal transplanted patients were not significantly different from the control group, although 2 peritoneal and 6 haemodialysed patients had subnormal values. Blood and bone marrow examination, performed in 64 patients, demonstrated no megaloblastic changes.