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Acute Depression of Serum Folate in Surgical Patients During Preoperative Infusion of Ethanol‐Free Parenteral Nutrition
Author(s) -
Tennant G. B.,
Smith R. C.,
Leinster S. J.,
O'Donnell J. E.,
Wardrop C. A. J.
Publication year - 1981
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1981.tb00493.x
Subject(s) - parenteral nutrition , calorie , medicine , hydrolysate , sorbitol , ethanol , depression (economics) , regimen , anesthesia , food science , chemistry , biochemistry , hydrolysis , economics , macroeconomics
Total parenteral nutrition for 48 h with Aminoplex solutions and a calorie source led to statistically similar, severe depression of the serum folate concentration (by 63–77%) irrespective of whether the calorie source contained ethanol, sorbitol, lipid or glucose. Folate levels were also depressed following infusion of other ethanol‐free regimens (Freamine and glucose, 59%; Vamin and glucose, 44%). Least depression (31%) followed use of Aminosol and glucose, a regimen based on casein hydrolysate. It seems important, therefore, to give prophylactic folate to all patients receiving parenteral nutrition, regardless of whether the calorie source is ethanol.