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Foetal Haemoglobin in Patients with Thyroid Disorders
Author(s) -
Davidson R. J.,
Bewsher P. D.,
Wood W. G.,
How J.
Publication year - 1981
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1981.tb00462.x
Subject(s) - thyroid , medicine , hormone , erythropoiesis , endocrinology , fetal hemoglobin , thyroid hormones , clinical significance , physiology , biology , fetus , anemia , pregnancy , genetics
The concentration of HbF and the number of HbF containing cells as measured by the sensitive fluorescent antiHbF antibody technique have been evaluated in 65 patients with treated and untreated thyroid dysfunction. The mean HbF concentration and mean percentage of F‐cells were both found to be significantly greater in untreated thyrotoxic patients than in those with treated thyrotoxicosis and treated or untreated hypothyroidism. The clinical relevance of these observations and their explanation by the modulating influence of thyroid hormones on erythropoiesis and Hb synthesis are briefly discussed.