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A Clinicopathological Study of 13 Danish Cases of Burkitt's Lymphoma
Author(s) -
Kerndrup G.,
Pallesen G.
Publication year - 1981
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1981.tb00458.x
Subject(s) - lymphoma , danish , medicine , pathology , lymph , cancer registry , incidence (geometry) , immunohistochemistry , stage (stratigraphy) , epidemiology , biology , philosophy , linguistics , physics , optics , paleontology
During a 4‐year period 24 cases of malignant non‐Hodgkin's lymphomas were proposed to be of the Burkitt‐type (BL) by at least 1 of 5 pathologists of the Lymphoma Registry in Jutland, Denmark. When the histological material was critically reviewed the diagnosis could be maintained in only 13 cases. 9 of the remaining 11 cases were immunoblastic lymphomas (IBL). Immunohistochemical stainings for cytoplasmic Ig‐chains revealed generally weak reactions in the cases of BL. A distinct B‐zone homing phenomenon first appearing in the lymphocytic mantle zone was observed in several lymph nodes from 2 patients with BL. In the BL‐group the correlation between initial clinical stage and survival was satisfactory, the 2‐year survival rate being 38 % in the total BL‐group. The incidence of BL was 2.1 % of the malignant non‐Hodgkin's lymphomas in the registry.