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Lennert's Lymphoma—Pathological and Immunological Studies in a Patient with Widespread Skin Involvement
Author(s) -
Huijgens P. C.,
Veldhuizen R.W.,
Veer M. B. van't,
Boonk W. J.,
Kalsbeek G. L.,
Langenhuijsen M. M. A. C.
Publication year - 1980
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1980.tb02760.x
Subject(s) - pathology , lymphoma , lymph , infiltration (hvac) , lymph node , pathological , medicine , prednisone , physics , thermodynamics
A 21‐year‐old male presented with a widespread skin infiltration characterized by irregularly elevated blue‐red plaques, generalized lymphadenopathy and enlarged parotid glands. Histological examination of the skin showed the characteristics of Lennert's lymphoma, as did the lymph nodes and parotid glands. Immunological studies on lymph node tissue revealed normal amounts of B‐ and T‐cells. The B‐cells were polyclonal. The T‐cells showed functional impairment in culture. Treatment with prednisone resulted in complete disappearance of all tumour manifestations within 6 weeks.