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Lineation of the Osmotic Fragility Curve of Erythrocytes
Author(s) -
Try K.
Publication year - 1980
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1980.tb02361.x
Subject(s) - erythrocyte fragility , fragility , lineation , chemistry , haemolysis , population , osmotic concentration , medicine , hemolysis , biology , biochemistry , immunology , paleontology , environmental health , tectonics
Lineation of the osmotic fragility curve by the method of Detraglia et al (1974) may be performed in most samples from a hospital population. Using the lineation procedure, the osmotic fragility may be tested by only 2 solutions of known osmolarity without any great loss of precision or accuracy. The osmotic fragility curve may be described by 2 values: C 50 = the concentration at which 50% of the erythrocytes are haemolyzed and C 50 ‐ C 80 = the decrease in concentration raising the fraction of haemolysis from 0.50 to 0.80.