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Chromosome Aberrations and Prognosis in Preleukaemia
Author(s) -
Panani Anna,
Papayannis A. G.,
Sioula E.
Publication year - 1980
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1980.tb02350.x
Subject(s) - karyotype , medicine , staining , chromosome , gastroenterology , g banding , cytogenetics , overall survival , pathology , biology , genetics , gene
24 patients with preleukaemia were cytogenetically studied by the G‐banding staining technique. All patients developed later frank acute non‐lymphocytic leukaemia and died. 13 patients had a completely normal karyotype (NN‐patients) with a median survival time of 8 months. 6 patients had both normal and abnormal metaphases (AN‐patients) with a median survival time of 18.5 months, while 5 patients had abnormal metaphases only (AA‐patients) with a median survival time of 3 months.