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Composition of Human Granulocytic Colonies as a Function of the Purification Stage of CSF
Author(s) -
Scarrà G. L. Bianchi,
Ajmar F.,
Barresi R.,
Ferraris A. M.,
Sessarego M.
Publication year - 1979
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1979.tb02870.x
Subject(s) - composition (language) , biology , function (biology) , immunology , chemistry , microbiology and biotechnology , andrology , medicine , philosophy , linguistics
Granulopoietic colonies grown in presence of human placental conditioned medium (HPCM), before and after partial purification, were characterized in terms of number of colonies, colony size and cellular composition. Our data demonstrate that the removal of inhibitors present in crude HPCM preparations results in a higher number of CFUc, which are wider in size and with different cellular composition.