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Massive Platelet Transfusion after Splenectomy in a Case of Myelofibrosis
Author(s) -
Toolis Francis,
Paton L.
Publication year - 1979
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1979.tb02868.x
Subject(s) - splenectomy , myelofibrosis , medicine , platelet , platelet transfusion , surgery , blood transfusion , spleen , bone marrow
A patient with myelofibrosis complicated by massive splenomegaly underwent splenectomy to alleviate the increasing transfusion requirements and iron overload. The platelets exhibited qualitative defects pre‐operatively. Following splenectomy the patient bled profusely and required massive blood and platelet transfusions. The postoperative haemorrhage was controlled by giving sufficient platelets to normalize the platelet aggregation.

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