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Three Different Acid Phosphatase Patterns in Leukaemic Lymphoid T‐Cells
Author(s) -
SøndergaardPetersen Helena,
Boesen Anne Marie
Publication year - 1979
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1979.tb02853.x
Subject(s) - acid phosphatase , pathology , phosphatase , enzyme , biology , chemistry , medicine , biochemistry
The acid phosphatase pattern was studied in leukaemic cells from 8 patients with T‐cell leukaemia (5 ALL and 3 CLL). In 2 cases the enzyme activity was focal granular with paranuclear localization as earlier demonstrated by other authors, while ‐ in contrast to these findings ‐ the enzyme activity in 4 cases demonstrated universal granular distribution. Almost all the cells from each patient showed the same picture. In the last 2 cases a mixed focal and universal granular pattern was observed, where half the cells possessed the focal form and the other half the universal form of granular activity. The two first‐mentioned patterns were observed in cases of T‐ALL as well as of T‐CLL, while the mixed pattern was seen only in cases of T‐ALL.