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Red Cell Inclusion Bodies in a Case of Preleukaemia
Author(s) -
Streichman S.,
Tatarski I.,
Manaster J.
Publication year - 1979
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1979.tb02807.x
Subject(s) - inclusion bodies , inclusion (mineral) , red cell , myeloid leukaemia , transcription factor , biology , cell , mechanism (biology) , transcription (linguistics) , gene , genetics , cancer research , medicine , chemistry , philosophy , recombinant dna , mineralogy , linguistics , epistemology
A 26‐year‐old female patient is reported in whom red cell inclusion bodies (Hb‐H) and thrombocytopenia appeared more than 5 years before the emergence of atypical chr. myeloid leukaemia. Attention is drawn to the fact that the recently uncovered mechanism of acquisition of Hb‐H (absence of transcription of specific genes) has previously been implicated in other biochemical changes typical of leukaemia.