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Human Erythropoiesis in Diffusion Chambers
Author(s) -
Walther F.,
Schopow K.
Publication year - 1979
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1979.tb02734.x
Subject(s) - erythropoiesis , andrology , diffusion , hypoxia (environmental) , chemistry , microbiology and biotechnology , biology , medicine , physics , oxygen , organic chemistry , anemia , thermodynamics
The diffusion chamber technique has been modified in order to stimulate human erythropiesis in addition to granulo and monocytopoiesis. The chamber recipient mice were subjected to a combination of 750 rad irradiation and long‐term non‐interrupted hypoxia (0.5 atm) without chamber retransplantation. 7 d after implantation erythroid cells started to increase, reaching a maximum of up to 70 % of the nucleated cells on day 12.