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Osteogenesis Imperfecta Associated with Multiple Myeloma
Author(s) -
Kutnowski M.,
Futeral B.,
Verbanck M.,
Naets J. P.,
Mullier J. P.
Publication year - 1979
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1979.tb00429.x
Subject(s) - osteogenesis imperfecta , bence jones protein , multiple myeloma , medicine , bone marrow , lesion , pathology , proteinuria , immunoglobulin light chain , antibody , immunology , kidney
In a case of osteogenesis imperfecta with multiple fractures already from childhood, myelomatosis was diagnosed at the age of 52 years because of a serum M‐component (IgG, lambda), Bence Jones proteinuria, myeloma cells in the bone marrow, and osteolytic skeletal lesions. She died 10 months later. A partial postmortem examination of a larger bone lesion confirmed the diagnosis.