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Reversible Severe Anaemia and Granulocytopenia Caused by Procainamide
Author(s) -
Beek Rudolf J. J.,
Bieger Robert,
Ottolander Gerard J.
Publication year - 1978
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1978.tb02505.x
Subject(s) - procainamide , discontinuation , medicine , haemolysis , erythropoiesis , anemia , immunology
A 64‐year‐old male developed severe anaemia during procainamide therapy. At the same time granulocytopenia was found. Discontinuation of procainamide led to complete recovery. Severe anaemia due to the use of procainamide is not well known. The available data indicate a maturation block of the erythropoiesis as the possible cause of the anaemia, perhaps in combination with an autoimmune haemolysis.