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Trisomy 8 in Acute Myeloid Leukaemia: A Non‐Random Event
Author(s) -
Philip Preben,
Wantzin Gunhild Lange,
Jensen Mogens Krogh,
Drivsholm Aage
Publication year - 1977
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1977.tb02086.x
Subject(s) - supernumerary , trisomy , chromosome , bone marrow , karyotype , trisomy 8 , biology , chromosome aberration , pathology , genetics , medicine , immunology , anatomy , gene
6 cases of AML with a supernumerary chromosome 8 as the only aberration in practically all bone marrow mitoses and 10 cases with a normal chromosome composition of the marrow cells were investigated in order to evaluate the possible influence of trisomy 8 on some clinical and cytokinetic parameters. No significant differences between the groups were found. In our laboratory a supernumerary chromosome 8 is present in 36% of AML cases with chromosomal aberrations.