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Jaundice and Hepatitis B Surface Antigen and Antibody in Greek Haemophiliacs
Author(s) -
Yannitsiotis A.,
Bossinakou I.,
Louizou C.,
Mandalaki T.
Publication year - 1977
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1977.tb01512.x
Subject(s) - jaundice , antibody , medicine , antigen , virology , hepatitis , immunology , gastroenterology
The incidence of hepatitis B surface antigen (HB s Ag) and antibody (HB s Ab) in 101 Greek multitransfused haemophiliacs with or without a previous history of jaundice was studied. Using the haemagglutination inhibition assay, HB s Ag was detected in 9.9 %, HB s Ab in 61.3 % and HB s Ag plus Ab in 11.8 % of the cases. The incidence of jaundice was 14.8 %. Liver function was tested by means of Normotest, SGOT, SGPT and serum protein electrophoresis. Abnormal values of liver function tests were found in 47 % of the patients. The abnormal findings were related to the presence of HB s Ag or Ab and to the history of jaundice. There was no significant difference between the various groups of patients.