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The Procoagulant Activity of Adipose Tissue
Author(s) -
Giercksky KarlErik
Publication year - 1977
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1977.tb01490.x
Subject(s) - adipose tissue , thromboplastin , tissue factor , in vivo , chemistry , in vitro , fibrin , platelet , endocrinology , medicine , biochemistry , biology , coagulation , immunology , microbiology and biotechnology
Homogenates of several rat and human adipose tissues contain procoagulant activity mainly due to the presence of tissue thromboplastin. Intravenous injections in rats of the active fraction from such homogenates cause the accumulation of 51 Cr‐labelled platelets and 125 I‐labelled fibrin in the lungs. The effect of phospholipase C and of specific antibodies against tissue thromboplastin on this procoagulant activity of adipose tissue has been studied in vitro and in vivo.