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Diagnosis of Intravascular Haemolysis Using Starch Gel Electrophoresis
Author(s) -
Ali M. A. M.,
Vanderlinden Brenda
Publication year - 1977
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1977.tb01484.x
Subject(s) - haemolysis , haptoglobin , electrophoresis , staining , starch , gel electrophoresis , hemolysis , chemistry , stain , chromatography , biochemistry , pathology , medicine , immunology
Starch gel electrophoresis was used to screen for intravascular haemolysis in 15 patients with clinical disorders known to be characterized by intravascular haemolysis. Decreased serum haptoglobins, increased free plasma haemoglobin and the presence of methaemalbumin was documented in all 15 patients. It is suggested that starch gel electrophoresis and staining with haem specific stain is a simple and reliable method for confirming intravascular haemolysis.