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Haemoglobin Synthesis following Injection of Iron‐poly (sorbitol‐gluconic acid) complex, Ferastral®
Author(s) -
Norrby Anders,
Sölvell Lennart
Publication year - 1977
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1977.tb01250.x
Subject(s) - gluconic acid , sorbitol , iron deficiency , chemistry , medicine , biochemistry , anemia
Ferastral®, a new iron‐poly (sorbitol‐gluconic acid) complex for parenteral use has been given to 22 patients with iron deficiency anaemia. The patients were divided in two groups. Group I received a suboptimal dose of Ferastral iron corresponding to 90% of the iron calculated to normalize the haemoglobin value. Increases in total haemoglobin and also blood losses were measured. The availability of the injected iron for haemoglobin synthesis ranged from 63% to 111%. Group II received an amount of Ferastral‐iron calculated to be necessary for normalization of the haemoglobin plus an additional 500 mg of Ferastral‐iron. In this group the haemoglobin increase was rapid. In 7 weeks 10 out of 14 patients had reached a normal haemoglobin level.