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Studies on the Placental Transfer in Rats of 59 Fe‐ and 14 C‐labelled Iron‐poly (sorbitol‐gluconic acid) complex
Author(s) -
LINDVALL SVEN,
DOMEIJ KRISTINA,
GAGNERMILCHERT INGALILL,
HELLSTRÖM VERA,
RYDELL GUNILLA
Publication year - 1977
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1977.tb01229.x
Subject(s) - sorbitol , gluconic acid , chemistry , biochemistry
The placental transfer of an iron‐poly (sorbitol‐gluconic acid) complex, Ferastral®, has been studied. By use of the 59 Fe‐, 14 C‐sorbitol, and 14 C‐gluconic acid labelled complexes it was shown that the passage of the iron moiety is related to foetal need and that only negligible amounts of 14 C from either 14 C‐sorbitol or 14 C‐gluconic acid labelled iron complexes were found in the foetus. This implies that the intact complex does not pass the placental barrier.