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Studies on the Effect of Parenteral Iron, Ferastral®, an Iron‐poly (sorbitol‐gluconic acid) complex, on Blood Coagulation in Man
Author(s) -
PLOEM JAN E.,
JEKEL MARIANNE
Publication year - 1977
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1977.tb01215.x
Subject(s) - gluconic acid , coagulation , sorbitol , chemistry , alum , biochemistry , medicine , organic chemistry
The possible influence of Ferastral®, an iron‐poly (sorbitol‐gluconic acid) complex, on blood coagulation in man was investigated. Ferastral added to plasma produced no changes in blood coagulation until a final concentration of 2 000 μg/ml (35.8 mmol/l) was used, when minimal changes in blood coagulation factors were observed. Five patients were given an intramuscular injection of 250 mg Ferastral. No changes in blood coagulation and thrombocyte function were observed up to 5 hours after the initial iron injection.