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Heparin Cofactor Activity and Antithrombin III Concentration in Plasma Related to Age and Sex
Author(s) -
ØDEGÅRD OLE RASMUS,
FAGERHOL MAGNE K.,
LIE METTE
Publication year - 1976
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1976.tb01183.x
Subject(s) - cofactor , antithrombin , heparin , heparin cofactor ii , chemistry , endocrinology , medicine , plasma concentration , biochemistry , enzyme
Heparin cofactor activity and antithrombin III (At‐III) concentration were measured in plasma from 219 healthy men and 177 women. Narrow ranges for heparin cofactor activity and At‐III concentration were found. The standard deviation for heparin cofactor activity in men and women was 8.6 and 10.1, respectively, for At‐III concentration 10.4 and 12.5 In men, mean heparin cofactor activity and mean At‐III concentration decreased significantly with increasing age. In women, mean heparin cofactor activity and mean At‐III concentration tended to be lower in fertile age. Hereditary At‐III deficiency was detected in one individual.