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Chromosome Abnormalities Identified by Banding Technique in a Patient with Acute Myeloid Leukaemia Complicating Hodgkin's Disease
Author(s) -
Lundh B.,
Mitelman F.,
Nilsson P. G.,
Stenstam M.,
Söderström N.
Publication year - 1975
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1975.tb02431.x
Subject(s) - karyotype , chromosome , myeloid , g banding , bone marrow , pathology , disease , biology , giemsa stain , immunology , medicine , cancer research , genetics , gene
Chromosome analyses using the Giemsa banding technique were performed on bone marrow cells in a patient with the association of Hodgkin's disease and acute myeloid leukaemia. All cells had an abnormal karyotype showing an extra chromosome No. 14, loss of one chromosome No. 17 and gain of one chromosome No. 18. These abnormalities are in many respects similar to the karyotype changes of lymphoid cells in malignant lymphomas, suggesting a pathogenetic relationship between the two disorders.