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Death of Blood Lymphocytes Studied by Supravital Dye Exclusion and 3 H‐Thymidine‐Autoradiography
Author(s) -
Claësson M. H.
Publication year - 1975
Publication title -
scandinavian journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0036-553X
DOI - 10.1111/j.1600-0609.1975.tb01081.x
Subject(s) - programmed cell death , lymphocyte , peripheral blood , population , thymidine , cell , chemistry , pathology , immunology , microbiology and biotechnology , biology , medicine , biochemistry , apoptosis , dna , environmental health
Lymphocyte death in peripheral blood of the mouse represents the death of both short‐ and long‐lived lymphocytes. The present data were based on lymphocyte separation, supravital dye exclusion, and autoradiographical procedures. The data strongly indicate that the frequency of intravascular cell death in the population of short‐lived lymphocytes is 4–10 times higher than the frequency of intravascular cell death of long‐lived lymphocytes.